Mmm... could be kinda neat. You could have like, a homestead kinda thing, and it'd be like in Animal Crossing where the point is to improve your home, except in order to do it you have to go out and get materials on your own, which could require some adventuring-type stuff. They could have a bunch of different skill trees for different things, like crafting skills to make furniture other ponies could buy, or combat skills for adventuring to get rarer materials, or any number of things. I can imagine them having a bunch of cooperative or competitive little games, maybe based on other talents - music stuff or other performances, so people can watch you play them, or cooking or stuff.
Maybe they could have a 'comfort' system added to your house too, so t's not just a matter of aesthetics, but you actually get bonuses for having a comfortable living space, to encourage players to ample all the different disciplines before they fall right into one without thinking.
And perhaps they could have events with the Mane Six, like Pinkie is throwing a party and is looking for the best performers, and whoever gets the best score in the performing minigames gets something special. Or cooperative events too, like a swarm of Parasprites comes into town, and the producers have to make stuff for the fighters to fend them off.
Man, this could be really cool. Gameloft should have made this shit.